Publications

Gretel B. Kamm, Juan C. Boffi, Kristina Zuza, Sara Nencini, Joaquin Campos, Katrin Schrenk-Siemens, Ivo Sonntag, Burçe Kabaglou, Muad Y. Abd El Hay, Anke Tappe-Theodor, Claudio Acuna, Thomas Kuner & Jan Siemens. A synaptic temperature sensor for body cooling. (under revision)

Mencacci NE, Brockmann MM, Dai J, Pajusalu S, Atasu B, Campos J, Pino G, Gonzalez-Latapi P, Patzke C, Schwake M, Tucci A, Pittman A, Simon-Sanchez J, Carvill GL, Balint B, Wiethoff S, Warner TT, Papandreou A, Soo A, Rein R, Kadastik-Eerme L, Puusepp S, Reinson K, Tomberg T, Hanagasi H, Gasser T, Bhatia KP, Kurian MA, Lohmann E, Õunap K, Rosenmund C, Südhof TC, Wood NW, Krainc D, Acuna C (2021)  Biallelic variants in TSPOAP1, encoding the active-zone protein RIMBP1, cause autosomal recessive dystonia. J Clin Invest. 2021 Apr 1;131(7):e140625. doi: 10.1172/JCI140625.

Plociennikowska A, Frankish J, Moraes T, Del Prete D, Kahnt F, Acuna C, Slezak M, Binder M, Bartenschlager R. TLR3 activation by Zika virus stimulates inflammatory cytokine production which dampens the antiviral response induced by RIG-I-like receptors. J Virol. 2021 Mar 3;95(10):e01050-20. doi: 10.1128/JVI.01050-20. Epub ahead of print. PMID: 33658344; PMCID: PMC8139665.

Mittal K, Schrenk-Siemens K. Lessons from iPSC research: Insights on peripheral nerve disease. Neurosci Lett. 2020 Nov 1;738:135358. doi: 10.1016/j.neulet.2020.135358. Epub 2020 Sep 6. PMID: 32898616.

Katrin Schrenk-Siemens, Jörg Pohle, Charlotte Rostock, Muad Abd El Hay, Ruby M. Lam, Marcin Szczot, Shiying Lu, Alexander T. Chesler, Jan Siemens; HESC-derived sensory neurons reveal an unexpected role for PIEZO2 in nociceptor mechanotransduction. bioRxiv, August 2019, doi: https://doi.org/10.1101/741660.

Rostock C*, Schrenk-Siemens K*, Pohle J, Siemens J. Human vs. Mouse Nociceptors - Similarities and Differences. Neuroscience 2018; 387:13-27. * these authors contributed equally to this work

Patzke C, Acuna C, Giam LR, Wernig M, Sudhof TC. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. J Exp Med2016;213(4):499-515.

Hanack C, Moroni M, Lima WC, Wende H, Kirchner M, Adelfinger L, Schrenk-Siemens K, Tappe-Theodor A, Wetzel C, Kuich PH, Gassmann M, Roggenkamp D, Bettler B, Lewin GR, Selbach M, Siemens J. GABA blocks pathological but not acute TRPV1 pain signals. Cell2015;160(4):759-770.

Schrenk-Siemens K, Wende H, Prato V, Song K, Rostock C, Loewer A, Utikal J, Lewin GR, Lechner SG, Siemens J. PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors. Nat Neurosci 2015;18(1):10-16.

Zhang Y, Pak C, Han Y, Ahlenius H, Zhang Z, Chanda S, Marro S, Patzke C, AcunaC, Covy J, Xu W, Yang N, Danko T, Chen L, Wernig M, Sudhof TC. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron2013;78(5):785-98.

Schrenk-Siemens K, Perez-Alcala S, Richter J, Lacroix E, Rahuel J, Korte M, Muller U, Barde YA, Bibel M. Embryonic stem cell-derived neurons as a cellular system to study gene function: lack of amyloid precursor proteins APP and APLP2 leads to defective synaptic transmission. Stem cells2008;26(8):2153-2163.

Bibel M, Richter J, Schrenk K, Tucker KL, Staiger V, Korte M, Goetz M, Barde YA. Differentiation of mouse embryonic stem cells into a defined neuronal lineage. Nature Neuroscience2004;7(9):1003-1009.

News

  • Pain Summer School

    "Chronic Pain and its affective consequences"

     

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  • International Satellite Symposium, "Neural Circuits of Pain - IV"

    Registration deadline extended to 5 April 2022!

     

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  • Latest research from Project A06

    (New paper published in Neuron)

     

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  • Junior Career Research Stipends

    Application deadline: 15. September 2021

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  • New monthly Data Seminar Series

    Data management and analysis updates, workshops & tutorials for the SFB 1158 community

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