Heidelberg Outpatient Center for Clinical Pain Research (HeiSIS)
Heidelberg Outpatient Center for Clinical Pain Research (HeiSIS)


The Heidelberg Outpatient Center for Clinical Pain Research (HeiSIS) is an independent research facility of the Section for Integrated Psychosomatics (headed by Prof. Wolfgang Eich) at the Department of General Internal Medicine and Psychosomatics. It is headed by Prof. (apl.) Dr. med. Jonas Tesarz and is dedicated to the development of innovative approaches to the diagnosis and therapy of chronic pain disorders.

The overall objective of the Heidelberg Center for Clinical Pain Research (HeiSIS) is the development and validation of new diagnostic and therapeutic methods for the treatment of chronic pain. The research outpatient clinic is dedicated to conducting scientific studies and is not a facility for the regular care of chronic pain patients. However, if the patient wishes, a further connection to our rheumatism pain outpatient clinic is possible. Here we attach great importance to a good cooperation with our referring physicians.

The bundling of interdisciplinary and internationally oriented research projects as well as the integrative connection to excellent clinical care structures enables cooperation across disciplines and locations so that new findings can be applied quickly. Our work is supported by public funding institutions such as the DFG and the BMBF. In addition to imaging techniques (MRT), genetic analyses, questionnaires and neurophysiological tests, we use innovative m-health technologies such as app-based intervention and virtual reality tools.


HeiSIS Website (currently only available in German):



  • New research findings from the Grinevich Lab (Project B02)

    (New paper published in Nature Neuroscience)


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  • New discovery in the pathophysiology of diabetic neuropathy

    (New paper published in Neuron)


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  • Gender equality in science and career development

    Supporting the work of the ALBA Network


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  • The Heidelberg Outpatient Center for Clinical Pain Research (HeiSIS)

    Congratulations to SFB 1158 Project Leader, Prof. Dr. Jonas Tesarz, on becoming the Head of a new facility in his department: The "Heidelberg Outpatient Center for Clinical Pain Research (HeiSIS)"


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  • Dr. Frauke Nees accepts new position in Kiel

    Congratulations to Dr. Frauke Nees, one of the Consortium's PIs, on her new position as the Director of the Institute of Medical Psychology and Medical Sociology and W3 Professorship for Medical Psychology and Behavioral Neurobiology in the Medical Faculty of the Christian-Albrechts University in Kiel.