Project-related publications

Godel T, Bäumer P, Pham M, Köhn A, Muschol N, Kronlage M, Kollmer J, Heiland S, Bendszus M, Mautner VF. Human dorsal-root-ganglion in-vivo morphometry and perfusion in Fabry painful neuropathy. Neurology. 2017;89:1274-1282.

Godel T, Pham M, Heiland S, Bendszus M, Bäumer P. Human dorsal-root-ganglion perfusion measured in-vivo by MRI. Neuroimage. 2016;141:81-87.

Hofmann L, Hose D, Grießhammer A, Blum R, Döring F, Dib-Hajj S, Waxman S, Sommer C, Wischmeyer E,Üçeyler N. Characterisation of a mouse model of Fabry disease. Elife. 2018;ePub 10/17. 

Klein T, Günther K, Kwong CK, Edenhofer F, Üçeyler N. Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene. Stem Cell Res. 2018;31:222-226.

Maier C, Baron R, Tölle TR, Binder A, Birbaumer N, Birklein F, Gierthmühlen J, Flor H, Geber C, Huge V, Krumova EK, Landwehrmeyer GB, Magerl W, Maihöfner C, Richter H, Rolke R, Scherens A, Schwarz A, Sommer C, Tronnier V, Üçeyler N, Valet M, Wasner G, Treede RD. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes. Pain. 2010;150:439-450. 

Pham M, Oikonomou D, Hornung B, Weiler M, Heiland S, Bäumer P, Kollmer J, Nawroth PPBendszus M.  MR neurography detects diabetic neuropathy early and with proximal predominance. Ann Neurol. 2015;78:939-948.

Siedler G, Káhn AK, Weidemann F, Wanner C,Sommer C, Üçeyler N. Dyshidrosis is associated with reduced amplitudes in electrically evoked pain-related potentials in women with Fabry disease. Clin Neurophysiol. 2019;130(4):528-536. doi: 10.1016/j.clinph.2019.01.008.

Üçeyler N, Urlaub D, Mayer C, Uehlein S, Held M, Sommer C. Tumor necrosis factor-α links heat and inflammation with Fabry pain. Mol Genet Metab. 2019. pii: S1096-7192(19)30169-6.

Üçeyler N, Biko L, Hose D, Hofmann L, Sommer C. Comprehensive and differential long-term characterization of the alpha-galactosidase A deficient mouse model of Fabry disease focusing on the sensory system and pain development. Mol Pain. 2016;12.

Üçeyler N, Magg B, Thomas P, Wiedmann S, Heuschmann P, Sommer C. A comprehensive Fabry-related pain questionnaire for adult patients. Pain. 2014;155:2301-2305. 

Üçeyler N, Ganendiran S, Kramer D, Sommer C. Characterization of pain in Fabry disease. Clin J Pain. 2014;30:915-920.

Üçeyler N, He L, Schönfeld D, Kahn AK, Reiners K, Hilz MJ, Breunig F, Sommer C. Small fibers in Fabry disease: baseline and follow-up data under enzyme replacement therapy. J Peripher Nerv Syst. 2011;16:304-314.

 

Other publications:

Üçeyler group:

Characterization of small fiber pathology in a mouse model of Fabry disease. Hofmann L, Hose D, Grießhammer A, Blum R, Döring F, Dib-Hajj S, Waxman S, Sommer C, Wischmeyer E, Üçeyler N. Elife. 2018 Oct 17;7. pii: e39300. doi: 10.7554/eLife.39300.

Sensory profiles and immune related expression patterns of patients with and without neuropathic pain after peripheral nerve lesion. Held M, Karl F, Vlckova E, Rajdova A, Escolano-Lozano F, Stetter C, Bharti R, Förstner KU, Leinders M, Dušek L, Birklein F, Bednarik J, Sommer C, Üçeyler N. Pain. 2019 May 22. doi: 10.1097/j.pain.0000000000001623. 

Detection of blood Gb3 deposits as a new tool for diagnosis and therapy monitoring in patients with classic Fabry disease. Üçeyler N, Böttger J, Henkel L, Langjahr M, Mayer C, Nordbeck P, Wanner C, Sommer C. J Intern Med. 2018 Oct;284(4):427-438. doi: 10.1111/joim.12801. 

Ullrich M, Weber M, Post AM, Popp S, Grein J, Zechner M, Guerrero González H, Kreis A, Schmitt AG, Üçeyler N, Lesch KP, Schuh K. OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency. Mol Psychiatry. 2018 Feb;23(2):444-458. doi: 10.1038/mp.2016.232.

Sommer group:

Doppler K, Appeltshauser L, Villmann C, Martin C, Peles E, Kramer HH, Haarmann A, Buttmann M, Sommer C. Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy. Brain 2016;139:2617-30.

Attal N, de Andrade DC, Adam F, Ranoux D, Teixeira MJ, Galhardoni R, Raicher I, Üçeyler N, Sommer C, Bouhassira D. Safety and efficacy of repeated injections of botulinum toxin A in peripheral neuropathic pain (BOTNEP): a randomised, double-blind, placebo-controlled trial. Lancet Neurol 2016;15:555-65.

Sommer C. Exploring pain pathophysiology in patients. Science 2016;354:588-92.

Sommer C. Peripheral neuropathies: Long-term opioid therapy in neuropathy: benefit or harm? Nat Rev Neurol 2017;13:516-7.

Pham group:

Hoffmann A, Dege T, Kunze R, Ernst AS, Lorenz H, Böhler LI, Korff T, Marti HH, Heiland S, Bendszus M, Helluy X, Pham MEarly Blood-Brain Barrier Disruption in Ischemic Stroke Initiates Multifocally Around Capillaries/Venules.Stroke.2018 Jun;49(6):1479-1487. 

Bäumer P, Kele H, Xia A, Weiler M, Schwarz D, Bendszus M, Pham MPosterior interosseous neuropathy: Supinator syndrome vs fascicular radial neuropathy.Neurology. 2016 Nov 1;87(18):1884-1891

Godel T, Pham M, Heiland S, Bendszus M, Bäumer P. Human dorsal-root-ganglion perfusion measured in-vivo by MRI.Neuroimage. 2016 Nov 1;141:81-87

Hoffmann A, Pfeil J, Alfonso J, Kurz FT, Sahm F, Heiland S, Monyer H, Bendszus M, Mueller AK, Helluy X, Pham M. Experimental Cerebral Malaria Spreads along the Rostral Migratory Stream.PLoS Pathog. 2016 Mar 10;12(3):e1005470

Pham M, Oikonomou D, Hornung B, Weiler M, Heiland S, Bäumer P, Kollmer J, Nawroth PP, Bendszus M. Magnetic resonance neurography detects diabetic neuropathy early and with Proximal Predominance.Ann Neurol. 2015 Dec;78(6):939-48

Kollmer J, Hund E, Hornung B, Hegenbart U, Schönland SO, Kimmich C, Kristen AV, Purrucker J, Röcken C, Heiland S, Bendszus M, Pham MIn vivo detection of nerve injury in familial amyloid polyneuropathy by magnetic resonance neurography.

Brain. 2015 Mar;138(Pt 3):549-62. doi: 10.1093/brain/awu344. Epub 2014 Dec 18.

News

  • New research findings from the Grinevich Lab (Project B02)

    (New paper published in Nature Neuroscience)

     

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  • New discovery in the pathophysiology of diabetic neuropathy

    (New paper published in Neuron)

     

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  • Gender equality in science and career development

    Supporting the work of the ALBA Network

     

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  • The Heidelberg Outpatient Center for Clinical Pain Research (HeiSIS)

    Congratulations to SFB 1158 Project Leader, Prof. Dr. Jonas Tesarz, on becoming the Head of a new facility in his department: The "Heidelberg Outpatient Center for Clinical Pain Research (HeiSIS)"

     

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  • Dr. Frauke Nees accepts new position in Kiel

    Congratulations to Dr. Frauke Nees, one of the Consortium's PIs, on her new position as the Director of the Institute of Medical Psychology and Medical Sociology and W3 Professorship for Medical Psychology and Behavioral Neurobiology in the Medical Faculty of the Christian-Albrechts University in Kiel.