Publications: 

Keller D, Láng T, Cservenák M, Puska G, Barna J, Csillag V, Farkas I, Zelena D, Dóra F, Küppers S, Barteczko L, Usdin TB, Palkovits M, Hasan MT, Grinevich V, Dobolyi A. A thalamo-preoptic pathway promotes social grooming in rodents. Curr Biol. 2022 Nov 7;32(21):4593-4606.e8. doi: 10.1016/j.cub.2022.08.062. Epub 2022 Sep 15.

Rashidi M, Maier E, Dekel S, Sütterlin M, Wolf RC, Ditzen B, Grinevich V, Herpertz SC. Peripartum effects of synthetic oxytocin: The good, the bad, and the unknown. Neurosci Biobehav Rev. 2022 Oct;141:104859. doi: 10.1016/j.neubiorev.2022.104859. Epub 2022 Sep 7.

Tang Y, Benusiglio D, Lefevre A, Küppers S, Lapies O, Kerspern D, Charlet A, Grinevich V. Viral vectors for opto-electrode recording and photometry-based imaging of oxytocin neurons in anesthetized and socially interacting rats. STAR Protoc. 2021 Dec 14;3(1):101032. doi: 10.1016/j.xpro.2021.101032. eCollection 2022 Mar 18.

Hopf, D., Schneider, E., Eckstein, M., Aguilar-Raab, C., & Ditzen, B. (2021). COVID-und Social Distancing bezogene Sorgen und ihre Beziehung zu psychischer und körperlicher ErkrankungPPmP-Psychotherapie· Psychosomatik· Medizinische Psychologie2021 Feb;71(2):57-60. doi: 10.1055/a-1347-7393. Epub 2021 Feb 18.

Schneider E, Müller L E, Ditzen B, Herpertz S.C, Bertsch K  (2021) Oxytocin and Social Anxiety: Interactions with Sex Hormones. PNEC  Jun;128:105224. doi: 10.1016/j.psyneuen.2021.105224. Epub 2021 Apr 18.

Wahis, J., Kerspern, D., Althammer, F., Baudon, A., Goyon, S., Hagiwara, D., Lefèvre, A.,  Boury-Jamot, B., Bellanger, B., Abatis, M., Silva da Gouveia, M., Benusiglio, D., Marina Eliava,  Rozov, A., Weinsanto, I., Knobloch-Bollmann, H.S., Wang, H., Pertin, M., Inquimbert, P., Pitzer, C., Siemens, J., Goumon, Y., Boutrel, B., Darbon, P., Lamy, C.M., Stern, J.E., Décosterd,I.,   Chatton, J-Y., Young, W.S., Stoop, R., Poisbeau, P., Grinevich, V.*, Charlet, A. (2021): Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents. Nature Neurosci., doi: 1038/s41593-021-00800-0.

de Moura Oliveira, V.E., Lukas. M., Wolf, H.N., Durante, E., Lorenz, A., Anna-Lena Mayer, A.-L., Bludau, A., Bosch, O.J., Grinevich, V., Egger, V., de Jong, T.R., Neumann, I.D. (2021): Concerted but segregated actions of oxytocin and vasopressin within the ventral and dorsal lateral septum determine female aggression. Nature Commun., in press.

Tang, Y., Benusiglio, D., Lefevre, A., Hilfiger, L., Althammer, F., Bludau, A., Hagiwara, D., Baudon, A., Darbon, P., Schimmer, J., Kirchner, M.K., Roy, R.K., Wang, S., Eliava, M., Wagner, S., Oberhuber, M., Conzelmann, K.K., Schwarz, M., Stern, J.E., Leng, G., Neumann, I.D., Charlet, A., Grinevich, V. (2020): Social touch promotes inter-female communication via activation of parvocellular oxytocin neurons. Nature Neurosci. doi: 10.1038/s41593-020-0674.

Duque-Wilckens, N., Torres, L., Yokoyama, S., Minie, V.A, Tran, A., Stela P. Petkova, S.P., Hao, R., Ramos-Maciel, S., Jackson, K., Pesavento, P., Iñiguez, S., Grinevich, V., Trainor, B.C. (2020): Extrahypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance. PNAS, https://doi.org/10.1073/pnas.2011890117

Schneider I, Boll S, Volman I, Roelofs K, Herpertz SC, Bertsch K. (2020) Oxytocin normalizes approach-avoidance behavior in women with borderline personality disorder. Frontiers in Psychiatry Mar 11;11:120

Grinevich, V., Neumann, I.D. (2020): Brain oxytocin: How puzzle stones from animal studies translate into psychiatry. Mol. Psychiatry https://doi.org/10.1038/s41380-020-0802-9.

Boll, S., Ueltzhoeffer, K., Roth, C., Betsch, K., Desch, S., Nees, F., Grinevich, V., Herpertz, S.C. (2020): Pain-modulating effects of oxytocin in patients with chronic low back pain. Neuropharmacology, 171:108105. doi: 10.1016/j.neuropharm.2020.108105.

Schneider, I., Schmitgen, M. M., Boll, S., Roth, C., Nees, F., Usai, K., Herpertz, S. C., & Wolf, R. C. (2020). Oxytocin modulates intrinsic neural activity in patients with chronic low back pain. European Journal of Pain, 24(5), 945-955.

Netser, S., Meyer, A., Magalnik, H., Zylbertal, A., de la Zerda, S.H., Briller, M., Bizer, A., Grinevich, V.*, Wagner, S. (2020): Distinct dynamics of social motivation drive different patterns of social behavior in Sprague Dawley rats and C57BL/6J mice. Nature Commun. doi: https://doi.org/10.1038/s41467-020-19569-0

Pfeifer, A. C., Schroeder-Pfeifer, P., Schneider, E., Schick, M., Heinrichs, M., Bodenmann, G., Ehlert, U., Herpertz, S. C., ... & Ditzen, B. (2020). Oxytocin and positive couple interaction affect the perception of wound pain in everyday life. Molecular Pain, 16, 1744806920918692.

Eckstein, M., Mamaev, I., Ditzen, B., & Sailer, U. (2020). Calming effects of touch in human, animal and robotic interaction–scientific state of the art and technical advances. Frontiers in Psychiatry, 11, 1153.

Herpertz, S. C., Schmitgen, M. M., Fuchs, C., Roth, C., Wolf, R. C., Bertsch, K., ... & Boll, S. (2019). Oxytocin effects on pain perception and pain anticipation. The Journal of Pain, 20(10), 1187-1198.

Boll S, Ueltzhoeffer K, Roth C, Bertsch K, Desch S, Nees F, Grinevich V, Herpertz SC. Oxytocin and positive couple interaction affect the perception of wound pain in everyday life. Neuropharmacology. 2020 Jul;171:108105. doi: 10.1016/j.neuropharm.2020.108105. Epub 2020 Apr 13.

Boll S*, Ueltzhoeffer K*, Roth C, , Bertsch K, Desch S, Nees F, Grinevich V, Herpertz SC. (2020) Pain-modulating effects of oxytocin in patients with chronic low back pain. Neuropharmacology Jul;171:108105.
 
Schneider I, Schmitgen MM, Boll S, Roth C, Nees F, Usuai K, Herpertz SC, Wolf RC. (2020) Oxytocin modulates intrinsic neural activity in patients with chronic low back pain. Eur J Pain. 2020 May;24(5):945-955. doi: 10.1002/ejp.1543. Epub 2020 Mar 9.

Pfeifer AC, Schroeder-Pfeifer P, Schneider E, Schick M, Heinrichs M, Bodenmann G, Ehlert U, Herpertz SC, Lauchli S, Eckstein M, Ditzen B. Oxytocin and positive couple interaction affect the perception of wound pain in everyday life. Mol Pain. 2020; 16: 1744806920918692.

Kluczniok D, Dittrich K, Hindi Attar C, Bödeker K, Roth M, Jaite C, Winter S, Herpertz SC, Röpke S, Heim C, Bermpohl F (2019) Oxytocin and Maltreatment Potential: Influence of maternal Depression, Borderline Personality Disorder and Experience of early Childhood Maltreatment. Nervenarzt;90(3):267-276
 
Reichl C, Kaess M, Fuchs A, Bödeker K, Hartmann A, Rujescu D, Parzer P, Resch F, Bermpohl F, Herpertz SC, & Brunner R (2019) Childhood adversity and parenting behavior: The role of oxytocin receptor gene polymorphisms. J Neural Transmission 126(6):777-787

Hasan, M.T., Althammer, F., da Silva Gouveia, M., Goyon, S., Eliava, M., Lefevre, A., Kerspern, D., Schimmer, J., Raftogianni, A., Wahis, J., Knobloch-Bollmann, H.S., Tang, Y., Liu, X., Jain, A., Chavant, V., Goumon, Y., Weislogel, J.-M., Hurlemann, R., Herpertz, S.C., Pitzer, C., Darbon, P., Dogbevia, G.K., Bertocchi, I., Larkum, M.E., Sprengel, R., Bading, H., Charlet, A. and Grinevich, V. (2019): A fear memory engram and its plasticity in the hypothalamic oxytocin system. Neuron, 103, 133-146. https://doi.org/10.1016/j.neuron.2019.04.029.

Ferretti, V., Maltese, F., Contarini, G., Marco Nigro, M., Alessandra Bonavia, A., Huiping, H., Gigliucci, V., Morelli, G., Scheggia, D., Managò, F., Castellani, G., Lefevre, A., Cancedda, L., Bice Chini, B., Grinevich, V*., and Papaleo, F. (2019) Oxytocin signaling in the central amygdala modulates emotion discrimination in mice. Cur. Biol., 29https://doi.org/10.1016/j.cub.2019.04.070

Herpertz SC*, Schmitgen M*, Fuchs C, Roth C, Wolf RC, Bertsch K, Grinevich V, Boll S. (2019) Oxytocin Effects on Pain Perception and Pain Anticipation. J Pain 20(10):1187-1198

Schatz, K.C., Brown, L.M., Barrett, A.R., Roth, L.C., Grinevich, V*., and Paul, M.J. (2019): Viral rescue of magnocellular vasopressin cells in adolescent Brattleboro rats ameliorates diabetes insipidus, but not the hypoaroused phenotype. Sci. Rep., doi: 10.1038/s41598-019-44776-1.

Grund, T., Tang, Y., Benusiglio, D., Althammer, F., Probst, S., Oppenlander, L., Neumann, I.D., and Grinevich, V. (2019). Chemogenetic activation of oxytocin neurons: Temporal dynamics, hormonal release, and behavioral consequences. Psychoneuroendocrinology106, 77-84.

Boll S, Almeida de Minas AC, Raftogianni A, Herpertz SC, Grinevich V. Oxytocin and Pain Perception: From Animal Models to Human Research. Neuroscience. 2018 Sep 1;387:149-161. doi: 10.1016/j.neuroscience.2017.09.041. Epub 2017 Sep 28.

Schuh-Hofer S, Eichhorn N, Grinevich V, Treede R-D (2018) Sleep deprivation related changes of plasma oxytocin in males and female contraceptive users depend on sex and correlate differentially with anx-iety and pain hypersensitivity. Front Behav Neuroscience 12: 161

Bertsch K, Gamer M, Schmidt B, Schmidinger I, Walther S, Kaestel T, Schnell K, Büchel C, Domes G, Herpertz SC. (2013) Oxytocin and reduction of social threat hypersensitivity in women with borderline person-ality disorder. Am J Psychiatry 170(10): p. 1169-77.

Boll S, Almeida de Minas AC, Raftogianni A, Herpertz SC, Grinevich V. (2018) Oxytocin and Pain Perception: From Animal Models to Human Research. Neuroscience 387: p. 149-161.

Eliava M, Melchior M, Knobloch-Bollmann HS, Wahis J, da Silva Gouveia M, Tang Y, Ciobanu AC, Triana del Rio R, Roth LC, Althammer F, Chavant V, Goumon Y, Gruber T, Busnelli M, Chini B, Tan L, Mitre M, Froemke RC, Chao MV, Giese G, Sprengel R, Kuner R, Poisbeau P, Seeburg PH, Stoop R, Charlet A,Grinevich V. (2016), A New Population of Parvocellular Oxytocin Neurons Controlling Magnocellular Neuron Activity and Inflammatory Pain Processing. Neuron 89(6): p. 1291-1304

Grinevich V, Stoop R (2018) Interplay between oxytocin and sensory systems in the orchestration of socio-emotional behaviour. Neuron 99:887-904

Kreuder A-K, Wassermann L, Wollseifer M, Ditzen B, Eckstein M, Stoffel-Wagner B, Hennig J, Hurlemann R, Scheele D. (2018), Oxytocin enhances the pain-relieving effects of social support in romantic couples. Hum Brain Mapp doi: 10.1002/hbm.24368

Menon R, Grund, T, Zoicas, Althammer F, Fiedler D, Biermeier V, Bosch OJ, Hiraoka Y, Nishimori K, Eliava M, Grinevich V, Neumann ID (2018) Enhanced oxytocin signaling in the lateral septum prevents social fear expression during lactation. Cur. Biology 28: 1066-1078

Lischke A*, Herpertz SC*, Berger C, Domes G, Gamer M. (2017) Divergent effects of oxytocin on (para-) limbic reactivity to emotional and non-emotional scenes in females with and without borderline per-sonality disorder. SCAN 12(11):1834

Ditzen B, Heinrichs M (2014) Psychobiology of social support: the social dimension of stress buffering. Restor Neurol Neurosci 32:149-62.

Ditzen B., Schaer, M., Bodenmann, J. G., Gabriel, B., Ehlert, U. & Heinrichs, M. (2009). Intranasal oxytocin increases positive communication and reduces cortisol levels during couple conflict. Biol Psychiatry 65: 728–731.

 

Other publications:

Iwasaki M, Lefevre A, Althammer F, Łąpieś O, Hilfiger L, Kerspern D, Melchior M, Küppers S, Krablicher Q, Patwell R, Herpertz SC, Ditzen B, Schönig K, Bartsch D, Stern JE, Darbon P, Grinevich V, Charlet A. A novel analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray. bioRxiv.2022.2002.2023.481531, 2022, DOI: https://doi.org/10.1101/2022.02.23.481531 (also in revision at Nature Communications)

 

News

  • New collaborative research results

    Published in Science

     

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  • ERC Synergy Grant 2022

    Congratulations to Prof. Dr. Valery Grinevich!

     

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  • John J. Bonica Prize of the IASP

    Congratulations to Prof. Dr. Rolf Detlef-Treede!

     

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  • New paper published in Nature

    Collaboration involving Projects A01, A03, B01, B06 and B08.

     

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  • Pain Summer School

    "Chronic Pain and its affective consequences"

     

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